A novel quantitative trait locus on mouse chromosome 18, "era1," modifies the entrainment of circadian rhythms.
| Author | |
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| Abstract | :
The mammalian circadian clock in the suprachiasmatic nuclei (SCN) of the hypothalamus conveys 24-h rhythmicity to sleep-wake cycles, locomotor activity, and other behavioral and physiological processes. The timing of rhythms relative to the light/dark (LD12:12) cycle is influenced in part by the endogenous circadian period and the time of day specific sensitivity of the clock to light. We now describe a novel circadian rhythm phenotype, and a locus influencing that phenotype, in a segregating population of mice. |
| Year of Publication | :
2007
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| Journal | :
Sleep
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| Volume | :
30
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| Issue | :
10
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| Number of Pages | :
1255-63
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| ISSN Number | :
0161-8105
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| URL | :
https://academic.oup.com/sleep/article-lookup/doi/10.1093/sleep/30.10.1255
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| DOI | :
10.1093/sleep/30.10.1255
|
| Short Title | :
Sleep
|
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